STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFS59930.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (527 aa)    
Predicted Functional Partners:
SFS59939.1
Dihydrolipoamide dehydrogenase.
 0.999
SFS59918.1
Pyruvate dehydrogenase E1 component beta subunit.
 
 0.998
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.997
SFS43617.1
Dihydrolipoamide dehydrogenase.
 0.994
SFS43651.1
2-oxoisovalerate dehydrogenase E1 component beta subunit.
 
 0.994
SFS43634.1
2-oxoisovalerate dehydrogenase E1 component alpha subunit.
 
 0.989
SFS97735.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.910
SFS83744.1
Glutamate synthase (NADPH/NADH) large chain.
     
 0.865
SFT02092.1
Acetaldehyde dehydrogenase / alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.856
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.842
Your Current Organism:
Halolactibacillus miurensis
NCBI taxonomy Id: 306541
Other names: DSM 17074, H. miurensis, Halolactibacillus miurensis Ishikawa et al. 2005, IAM 15247, JCM 21699, NBRC 100873, NRIC 0633, strain M23-1
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