STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D8TXZ3_VOLCAUncharacterized protein. (327 aa)    
Predicted Functional Partners:
D8TTP6_VOLCA
Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.
    
 0.997
D8U0K1_VOLCA
Uncharacterized protein.
    
 0.997
fenA
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.997
fenB
Nuclease, Rad2 family.
  
 0.995
D8TQ62_VOLCA
PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.
   
 0.994
pcn1b
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.993
D8TNV1_VOLCA
SAS-6_N domain-containing protein.
   
 0.993
D8TW12_VOLCA
Uncharacterized protein.
   
 0.993
D8TX09_VOLCA
Helicase ATP-binding domain-containing protein.
   
 0.992
D8U601_VOLCA
Uncharacterized protein.
  
 0.992
Your Current Organism:
Volvox carteri
NCBI taxonomy Id: 3068
Other names: V. carteri f. nagariensis, Volvox carteri f. nagariensis, Volvox carteri f. nagariensis M.O.P.Iyengar
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.