node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATM1 | DRE2 | Q2HIE9 | Q2GYB6 | Iron-sulfur clusters transporter ATM1, mitochondrial; Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Hydrolyzes ATP. Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity). | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | 0.585 |
ATM1 | NAR1 | Q2HIE9 | Q2HEF1 | Iron-sulfur clusters transporter ATM1, mitochondrial; Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Hydrolyzes ATP. Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity). | Cytosolic Fe-S cluster assembly factor NAR1; Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity). | 0.623 |
ATM1 | NBP35 | Q2HIE9 | Q2H317 | Iron-sulfur clusters transporter ATM1, mitochondrial; Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Hydrolyzes ATP. Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity). | Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.544 |
CHGG_00047 | CHGG_01092 | Q2HIA7 | Q2HFB2 | NADH-ubiquinone oxidoreductase 23 kDa subunit. | NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | 0.999 |
CHGG_00047 | CHGG_05606 | Q2HIA7 | Q2H6V9 | NADH-ubiquinone oxidoreductase 23 kDa subunit. | Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). | 0.816 |
CHGG_00047 | CHGG_09047 | Q2HIA7 | Q2GSK7 | NADH-ubiquinone oxidoreductase 23 kDa subunit. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. | 0.999 |
CHGG_00047 | CHGG_09244 | Q2HIA7 | Q2GS10 | NADH-ubiquinone oxidoreductase 23 kDa subunit. | Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. | 0.999 |
CHGG_00047 | CHGG_10220 | Q2HIA7 | Q2GP84 | NADH-ubiquinone oxidoreductase 23 kDa subunit. | NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. | 0.999 |
CHGG_00047 | NBP35 | Q2HIA7 | Q2H317 | NADH-ubiquinone oxidoreductase 23 kDa subunit. | Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.559 |
CHGG_00882 | NBP35 | Q2HFX2 | Q2H317 | Histidine biosynthesis trifunctional protein. | Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.849 |
CHGG_01092 | CHGG_00047 | Q2HFB2 | Q2HIA7 | NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | NADH-ubiquinone oxidoreductase 23 kDa subunit. | 0.999 |
CHGG_01092 | CHGG_05606 | Q2HFB2 | Q2H6V9 | NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). | 0.970 |
CHGG_01092 | CHGG_09047 | Q2HFB2 | Q2GSK7 | NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. | 0.999 |
CHGG_01092 | CHGG_09244 | Q2HFB2 | Q2GS10 | NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. | 0.999 |
CHGG_01092 | CHGG_10220 | Q2HFB2 | Q2GP84 | NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. | 0.999 |
CHGG_01092 | NBP35 | Q2HFB2 | Q2H317 | NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.526 |
CHGG_05606 | CHGG_00047 | Q2H6V9 | Q2HIA7 | Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). | NADH-ubiquinone oxidoreductase 23 kDa subunit. | 0.816 |
CHGG_05606 | CHGG_01092 | Q2H6V9 | Q2HFB2 | Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). | NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | 0.970 |
CHGG_05606 | CHGG_09244 | Q2H6V9 | Q2GS10 | Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). | Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. | 0.748 |
CHGG_05606 | CHGG_10220 | Q2H6V9 | Q2GP84 | Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). | NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. | 0.645 |