STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSE1Class E vacuolar protein-sorting machinery protein HSE1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB). (713 aa)    
Predicted Functional Partners:
VPS27
Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
  
0.986
CHGG_09109
Polyubiquitin.
    
 0.894
CHGG_08471
Uncharacterized protein.
   
 0.845
CHGG_09035
Uncharacterized protein.
   
 0.842
CHGG_09882
MPN domain-containing protein.
    
 0.832
CHGG_01715
Uncharacterized protein.
   
 0.808
CHGG_09220
Uncharacterized protein.
    
 0.804
CHGG_01130
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.742
CHGG_08895
Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.
 
 
    0.724
CHGG_05541
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
     
 0.707
Your Current Organism:
Chaetomium globosum
NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.