node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SBV25552.1 | SBV26364.1 | GA0070620_1029 | GA0070620_1852 | Proline iminopeptidase; Belongs to the peptidase S33 family. | Pimeloyl-ACP methyl ester carboxylesterase. | 0.681 |
SBV25552.1 | proC | GA0070620_1029 | GA0070620_6081 | Proline iminopeptidase; Belongs to the peptidase S33 family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.871 |
SBV26364.1 | SBV25552.1 | GA0070620_1852 | GA0070620_1029 | Pimeloyl-ACP methyl ester carboxylesterase. | Proline iminopeptidase; Belongs to the peptidase S33 family. | 0.681 |
SBV26364.1 | proC | GA0070620_1852 | GA0070620_6081 | Pimeloyl-ACP methyl ester carboxylesterase. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.789 |
SBV27262.1 | SBV29409.1 | GA0070620_2769 | GA0070620_4981 | Ornithine cyclodeaminase. | L-proline dehydrogenase. | 0.836 |
SBV27262.1 | proC | GA0070620_2769 | GA0070620_6081 | Ornithine cyclodeaminase. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.813 |
SBV27785.1 | SBV29409.1 | GA0070620_3315 | GA0070620_4981 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | L-proline dehydrogenase. | 0.987 |
SBV27785.1 | proA | GA0070620_3315 | GA0070620_5057 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.873 |
SBV27785.1 | proB | GA0070620_3315 | GA0070620_5058 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.871 |
SBV27785.1 | proC | GA0070620_3315 | GA0070620_6081 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.879 |
SBV28725.1 | ilvC | GA0070620_4279 | GA0070620_2960 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.565 |
SBV28725.1 | leuD | GA0070620_4279 | GA0070620_2933 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.612 |
SBV28725.1 | proC | GA0070620_4279 | GA0070620_6081 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.698 |
SBV29409.1 | SBV27262.1 | GA0070620_4981 | GA0070620_2769 | L-proline dehydrogenase. | Ornithine cyclodeaminase. | 0.836 |
SBV29409.1 | SBV27785.1 | GA0070620_4981 | GA0070620_3315 | L-proline dehydrogenase. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.987 |
SBV29409.1 | proA | GA0070620_4981 | GA0070620_5057 | L-proline dehydrogenase. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.618 |
SBV29409.1 | proB | GA0070620_4981 | GA0070620_5058 | L-proline dehydrogenase. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.648 |
SBV29409.1 | proC | GA0070620_4981 | GA0070620_6081 | L-proline dehydrogenase. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.956 |
ilvC | SBV28725.1 | GA0070620_2960 | GA0070620_4279 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.565 |
ilvC | leuD | GA0070620_2960 | GA0070620_2933 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.985 |