Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000001119Ring finger protein 111. (981 aa)    
Predicted Functional Partners:
ENSOMEP00000033039
Small ubiquitin-related modifier.
    
 0.869
LOC112156701
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.850
ube2n
Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.850
smad7
Mothers against decapentaplegic homolog.
   
 0.836
smad6
Mothers against decapentaplegic homolog.
   
 0.836
LOC112160358
Mothers against decapentaplegic homolog.
   
 0.836
ENSOMEP00000002833
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.812
ENSOMEP00000020966
Ribosomal protein S27a.
    
 0.791
ENSOMEP00000035400
Ubiquitin-like domain-containing protein.
    
  0.702
sec63
SEC63 homolog, protein translocation regulator.
    
 
 0.696
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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