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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scg5Secretogranin V. (263 aa)    
Predicted Functional Partners:
ENSOMEP00000004753
Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.
   
 
 0.859
scg3
Secretogranin III.
   
  
 0.652
LOC112147081
Secretogranin II (chromogranin C), b.
   
  
 0.622
pcsk7
Proprotein convertase subtilisin/kexin type 7; Belongs to the peptidase S8 family.
   
 
 0.585
cpe
Carboxypeptidase E.
   
  
 0.583
pam
Peptidylglycine alpha-amidating monooxygenase.
   
  
 0.574
ENSOMEP00000017251
Rho GTPase activating protein 11A.
 
    
 0.570
mbtps1
Membrane-bound transcription factor peptidase, site 1.
   
 
 0.545
LOC112151630
Retinol dehydrogenase 12, like; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.538
pcsk1
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
   
 
 0.514
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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