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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
setd1bSET domain containing 1B, histone lysine methyltransferase a. (1802 aa)    
Predicted Functional Partners:
rbbp5
Retinoblastoma binding protein 5.
    
 0.978
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.978
ENSOMEP00000007787
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 0.948
ENSOMEP00000020599
SET domain containing 2, histone lysine methyltransferase.
   
0.900
LOC112158908
Uncharacterized protein.
   
 0.890
cxxc1
CXXC finger protein 1b.
   
 0.890
ENSOMEP00000003686
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.888
wdr5
WD repeat domain 5.
   
 0.888
plod2
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2.
    
  0.882
wdr82
WD repeat domain 82.
   
 0.880
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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