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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tollipToll interacting protein. (276 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.989
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
     
 0.981
LOC112136553
Toll-like receptor 18.
    
 0.979
ENSOMEP00000009965
Protein kinase domain-containing protein.
   
 0.973
LOC112155905
TIR domain-containing protein; Belongs to the Toll-like receptor family.
    
 0.911
LOC112156495
TIR domain-containing protein; Belongs to the Toll-like receptor family.
    
 0.911
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.894
irak4
Interleukin-1 receptor-associated kinase 4.
   
 0.857
ENSOMEP00000026651
Protein kinase domain-containing protein.
   
 0.857
il1rap
Uncharacterized protein.
    
 0.825
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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