close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000001494WD_REPEATS_REGION domain-containing protein. (277 aa)    
Predicted Functional Partners:
ENSOMEP00000001505
Uncharacterized protein.
 
    
 0.904
ENSOMEP00000019238
FYVE-type domain-containing protein.
 
      0.900
ENSOMEP00000019255
Uncharacterized protein.
 
      0.899
smpd2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
     
 0.642
rbsn
Rabenosyn, RAB effector.
     
 0.607
vps45
Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family.
   
 
  0.580
wdr31
WD repeat domain 31.
    
 0.571
rack1
Receptor for activated C kinase 1.
    
0.571
smpd3
Sphingomyelin phosphodiesterase 3, neutral.
     
 0.553
ENSOMEP00000009837
Pleckstrin homology domain containing, family G (with RhoGef domain) member 7.
    
 0.532
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
Server load: low (28%) [HD]