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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcsk1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (769 aa)    
Predicted Functional Partners:
ENSOMEP00000024051
Fras1 related extracellular matrix 1a.
    
 0.764
ENSOMEP00000025575
Fras1 related extracellular matrix 1b.
    
 0.764
rxfp2
Relaxin family peptide receptor 2a.
  
 0.760
ENSOMEP00000020844
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
 0.760
rxfp1
Relaxin family peptide receptor 1.
  
 0.760
lgr4
Leucine-rich repeat containing G protein-coupled receptor 4.
  
 0.760
LOC112162582
Uncharacterized protein.
     
 0.714
POMC
Proopiomelanocortin.
     
 0.714
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.628
LOC112153519
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.628
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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