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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grnGranulin b. (766 aa)    
Predicted Functional Partners:
ENSOMEP00000034591
Citrate synthase; Belongs to the citrate synthase family.
   
   0.768
drg1
Developmentally regulated GTP binding protein 1.
    
   0.762
pole2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
    
   0.762
cunh15orf40
Zgc:193812.
    
   0.762
ENSOMEP00000033954
Zgc:103697.
    
   0.762
LOC112152409
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 0.751
ctsz
Cathepsin Z; Belongs to the peptidase C1 family.
   
 0.751
LOC112158204
Cathepsin Bb; Belongs to the peptidase C1 family.
   
 0.731
LOC112160419
Cathepsin Ba; Belongs to the peptidase C1 family.
   
 0.731
ctsf
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.711
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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