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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000001682F11 receptor, tandem duplicate 1. (282 aa)    
Predicted Functional Partners:
tjp2
Tight junction protein 2a (zona occludens 2); Belongs to the MAGUK family.
   
 0.964
ENSOMEP00000013980
Tight junction protein 1b; Belongs to the MAGUK family.
   
 0.961
LOC112160469
Tight junction protein 1a; Belongs to the MAGUK family.
   
 0.961
ENSOMEP00000022368
Afadin, adherens junction formation factor a.
    
 0.946
ENSOMEP00000032221
Uncharacterized protein.
    
 0.946
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6.
     
 0.938
jam2
Junctional adhesion molecule 2a.
    
0.933
LOC112140819
Junctional adhesion molecule 3b.
    
0.926
pard3
Par-3 family cell polarity regulator alpha, b.
    
 0.923
PARD3
Par-3 family cell polarity regulator.
    
 0.923
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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