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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctscCathepsin C; Belongs to the peptidase C1 family. (453 aa)    
Predicted Functional Partners:
bcl2
BCL2 apoptosis regulator b.
   
 
 0.957
LOC112144934
Uncharacterized protein.
     
 0.896
LOC112154285
Baculoviral IAP repeat containing 5a.
     
 0.891
LOC112158719
Baculoviral IAP repeat containing 5b.
     
 0.891
LOC112142434
Baculoviral IAP repeat containing 2.
     
 0.889
bcl2l1
BCL2 like 1.
     
 0.880
ctsf
Cathepsin F; Belongs to the peptidase C1 family.
   
0.871
ctsd
Cathepsin D; Belongs to the peptidase A1 family.
   
 0.851
LOC112158204
Cathepsin Bb; Belongs to the peptidase C1 family.
   
0.825
LOC112160419
Cathepsin Ba; Belongs to the peptidase C1 family.
   
0.825
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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