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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000001690Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1985 aa)    
Predicted Functional Partners:
ENSOMEP00000035779
Uncharacterized protein.
   
 0.998
scn2b
Sodium channel, voltage-gated, type II, beta.
   
 0.914
LOC112161060
Ig-like domain-containing protein.
   
 0.909
LOC112136535
Sodium channel, voltage-gated, type I, beta a.
   
 0.909
LOC112149821
Sodium channel, voltage-gated, type IV, beta a.
    
 0.814
wdr35
WD repeat-containing protein 35.
    
 0.756
IFT122
Intraflagellar transport 122.
   
 0.750
wdr19
WD repeat domain 19.
    
 0.745
LOC112138737
Sodium channel, voltage-gated, type IV, beta b.
    
 0.741
LOC112136712
Si:ch211-225p5.8.
     
  0.738
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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