STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbrg4Transforming growth factor beta regulator 4. (632 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
   
 
 0.983
LOC112147267
AP-1 complex subunit gamma.
    
 0.881
ap1g1
AP-1 complex subunit gamma.
    
 0.881
ENSOMEP00000001067
AP complex subunit beta.
    
 0.872
LOC112142550
AP complex subunit beta.
    
 0.872
ap4b1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.850
ENSOMEP00000031400
Adaptor related protein complex 4 subunit epsilon 1.
    
 0.836
LOC112150846
Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.
    
 0.777
ENSOMEP00000014704
AP4E_app_platf domain-containing protein.
    
 0.777
ap1m1
AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    
 0.777
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.