STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC112157702ADAM metallopeptidase domain 17b. (838 aa)    
Predicted Functional Partners:
ENSOMEP00000008043
Notch receptor 1b.
    
 0.942
LOC112163451
Notch receptor 1a.
    
 0.942
LOC112146115
Notch receptor 3.
    
 0.935
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 
 0.931
LOC112149788
ADAM metallopeptidase domain 17a.
  
  
 
0.926
LOC112136930
Notch receptor 2.
    
 0.904
LOC112160714
Uncharacterized protein.
     
0.810
TIMP2
TIMP metallopeptidase inhibitor 2.
    
 
 0.707
LOC112146029
TIMP metallopeptidase inhibitor 2b.
    
 
 0.707
LOC112139461
Tumor necrosis factor a (TNF superfamily, member 2).
     
 0.699
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.