STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC112142788Estrogen receptor 2b. (668 aa)    
Predicted Functional Partners:
ENSOMEP00000033103
Uncharacterized protein.
    
 0.930
ENSOMEP00000013484
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.892
pgr
Progesterone receptor.
   
0.879
LOC112146043
E1A binding protein p300 b.
    
 0.876
LOC112153984
E1A binding protein p300 a.
    
 0.876
nrip1
Nuclear receptor interacting protein 1b.
    
 0.872
LOC112158236
V-fos FBJ murine osteosarcoma viral oncogene homolog Ab.
    
 0.857
ENSOMEP00000004505
CREB binding protein a.
    
 0.815
crebbp
CREB binding protein b.
    
 0.815
ENSOMEP00000000883
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
    
 0.811
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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