STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC112157004SH3 domain containing GRB2 like 2a, endophilin A1. (363 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
   
 0.988
egfr
Receptor protein-tyrosine kinase.
    
 0.903
LOC112151354
Receptor protein-tyrosine kinase.
    
 0.900
LOC112142874
Uncharacterized protein.
    
 0.888
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.886
ENSOMEP00000000147
SH3-domain kinase binding protein 1.
   
 
0.881
LOC112143591
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.881
LOC112152311
Tyrosine-protein kinase receptor.
    
  0.875
ENSOMEP00000032841
Tyrosine-protein kinase receptor.
    
  0.870
fgfr3
Fibroblast growth factor receptor.
   
 
  0.864
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.