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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
unc45bUnc-45 myosin chaperone B. (930 aa)    
Predicted Functional Partners:
LOC112137228
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.
   
 
 0.837
ENSOMEP00000035769
Heat shock protein 90, alpha (cytosolic), class B member 1.
   
 
 0.827
ENSOMEP00000003624
Uncharacterized protein.
   
 
 0.700
ENSOMEP00000009025
TNF receptor-associated protein 1.
   
 
 0.700
LOC112140338
TSC complex subunit 1b.
   
 
 0.700
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 
 0.688
LOC112148532
SET and MYND domain containing 1b.
   
  
 0.644
myo1e
Myosin IEa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.642
LOC112136585
Myosin IEb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.642
LOC112150877
Myosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.642
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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