STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptxAprataxin. (357 aa)    
Predicted Functional Partners:
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1.
    
 
 0.875
xrcc4
Uncharacterized protein.
    
 
 0.859
rae1
Ribonucleic acid export 1.
   
    0.752
tdp1
Tyrosyl-DNA phosphodiesterase 1.
    
 
 0.750
ENSOMEP00000023971
Eukaryotic translation initiation factor 2B, subunit 1 alpha; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
    0.732
ENSOMEP00000020858
Poly [ADP-ribose] polymerase.
   
 
 0.698
lig3
DNA ligase.
   
 
 0.665
tonsl
Tonsoku-like, DNA repair protein.
   
  
 0.648
polb
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
   
 
 0.639
ENSOMEP00000008661
BRCT domain-containing protein.
   
 
 0.638
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.