close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC112139381Retinal outer segment membrane protein 1a. (348 aa)    
Predicted Functional Partners:
LOC112153705
Retinal outer segment membrane protein 1b.
  
  
0.878
met
MET proto-oncogene, receptor tyrosine kinase.
    
  0.627
ENSOMEP00000021604
Macrophage stimulating 1 receptor b.
    
  0.627
LOC112145561
Macrophage stimulating 1 receptor a.
    
  0.627
LOC112160530
Si:dkeyp-86f7.4.
    
 
 0.599
LOC112159783
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
   
  
 0.592
LOC112144907
Transforming growth factor, alpha.
     
 0.578
LOC112144202
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
   
  
 0.577
LOC112152144
PNPLA domain-containing protein.
      
 0.526
ppp1cb
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
      
 0.491
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.