STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000007410DMAP-interaction domain-containing protein. (336 aa)    
Predicted Functional Partners:
ENSOMEP00000009786
Aminoadipate-semialdehyde dehydrogenase.
  
 0.905
coasy
CoA synthase.
  
 
 0.861
palb2
PALB2_WD40 domain-containing protein.
  
 0.844
ndufab1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.844
nup93
Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.
   
 0.825
ENSOMEP00000024663
Hydroxysteroid dehydrogenase like 2.
  
 0.804
med23
Mediator complex subunit 23.
    
 0.760
ENSOMEP00000034591
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.755
med15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.745
ENSOMEP00000034470
Mediator complex subunit 17.
    
 0.738
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.