STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
snapinSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (133 aa)    
Predicted Functional Partners:
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6.
   
 
  0.982
gak
Cyclin G associated kinase.
   
 
  0.982
bloc1s1
Biogenesis of lysosomal organelles complex-1, subunit 1.
   
 0.980
dtnbp1
Dystrobrevin binding protein 1b.
   
 0.979
bloc1s2
Biogenesis of lysosomal organelles complex-1, subunit 2.
   
 
 0.951
bloc1s6
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
    
 0.886
ENSOMEP00000023058
Mothers against decapentaplegic homolog.
 
   
 0.845
bloc1s3
Biogenesis of lysosomal organelles complex-1, subunit 3.
    
 0.824
bloc1s5
Biogenesis of lysosomal organelles complex-1, subunit 5, muted.
   
 0.796
arl5b
ADP-ribosylation factor-like 8; Belongs to the small GTPase superfamily. Arf family.
     
 0.783
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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