STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000008247VGCC_alpha2 domain-containing protein. (183 aa)    
Predicted Functional Partners:
CACNA2D4
Calcium voltage-gated channel auxiliary subunit alpha2delta 4.
 
      0.862
ENSOMEP00000018415
Calcium channel, voltage-dependent, alpha 2/delta subunit 4b.
 
      0.858
ENSOMEP00000007532
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
    
 0.799
LOC112146558
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
    
 0.799
cacnb2
Calcium channel, voltage-dependent, beta 2a.
   
 0.711
LOC112136806
Calcium channel, voltage-dependent, beta 4b subunit.
   
 0.711
LOC112147673
Calcium channel, voltage-dependent, beta 2b.
   
 0.711
LOC112154990
Calcium channel, voltage-dependent, beta 4a subunit.
   
 0.711
cacnb1
Calcium channel, voltage-dependent, beta 1 subunit.
   
 0.711
LOC112159101
Calcium channel, voltage-dependent, beta 3a.
   
 0.711
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.