STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000008450Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (124 aa)    
Predicted Functional Partners:
LOC112163170
Occludin a.
   
 0.780
LOC112160469
Tight junction protein 1a; Belongs to the MAGUK family.
   
 0.741
ENSOMEP00000022462
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
 
0.741
LOC112144217
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
0.737
ENSOMEP00000013980
Tight junction protein 1b; Belongs to the MAGUK family.
   
 0.727
LOC112163009
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
 
0.723
ENSOMEP00000001830
Tight junction protein 3; Belongs to the MAGUK family.
   
 0.704
ENSOMEP00000001837
Uncharacterized protein.
   
 0.704
cldn19
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
0.699
CLDN8
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
 
0.698
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.