STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC112143213C-type lectin domain family 3, member Ba. (190 aa)    
Predicted Functional Partners:
LOC112139461
Tumor necrosis factor a (TNF superfamily, member 2).
    
   0.724
ENSOMEP00000018249
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
   0.724
LOC112162673
Uncharacterized protein.
   
 0.661
itih5
Inter-alpha-trypsin inhibitor heavy chain 5.
   
 0.606
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.562
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
    
 0.560
tnn
Tenascin N.
    
 0.555
LOC112142074
Tenascin C.
    
  0.529
tnr
Tenascin R (restrictin, janusin).
    
  0.529
ENSOMEP00000031303
Zmp:0000000846.
    
  0.529
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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