STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frs2Fibroblast growth factor receptor substrate 2b. (525 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.961
fgfr2
Fibroblast growth factor receptor.
    
 0.911
LOC112148278
Fibroblast growth factor receptor.
    
 0.894
fgfr3
Fibroblast growth factor receptor.
    
 0.889
LOC112142653
Fibroblast growth factor receptor 4.
    
 0.889
LOC112162937
Fibroblast growth factor receptor.
    
 0.875
ENSOMEP00000031678
Ret proto-oncogene receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.840
ENSOMEP00000006832
Son of sevenless homolog 1 (Drosophila).
   
 0.822
ENSOMEP00000021243
Son of sevenless homolog 2 (Drosophila).
   
 0.822
ENSOMEP00000011943
Protein tyrosine phosphatase non-receptor type 6.
    
 0.819
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.