STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
f2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (617 aa)    
Predicted Functional Partners:
serpinc1
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
  
 0.999
fga
Fibrinogen alpha chain.
   
 0.998
fgb
Fibrinogen beta chain.
   
 0.998
fgg
Fibrinogen gamma chain.
   
 0.997
serpind1
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
  
 0.997
LOC112162868
Coagulation factor II thrombin receptor.
    
 0.995
LOC112144325
Protein C (inactivator of coagulation factors Va and VIIIa), a.
  
0.993
F2RL3
F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
 0.991
ENSOMEP00000004688
Coagulation factor II (thrombin) receptor-like 2.
    
 0.988
F2RL2
Coagulation factor II thrombin receptor like 2.
    
 0.988
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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