AREL1 protein (Oryzias melastigma) - STRING interaction network

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Score

AREL1

Apoptosis resistant E3 ubiquitin protein ligase 1. (1019 aa)

Predicted Functional Partners:

trip12

0.803

ENSOMEP00000002833

0.773

fau

0.741

ENSOMEP00000020966

0.704

atg7

0.639

mtx2

0.613

ENSOMEP00000035400

0.608

mtx3

0.603

zfand4

0.599

LOC112156226

0.598

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AREL1	ENSOMEP00000002833	ENSOMEP00000018519	ENSOMEP00000002833	Apoptosis resistant E3 ubiquitin protein ligase 1.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.773
AREL1	ENSOMEP00000020966	ENSOMEP00000018519	ENSOMEP00000020966	Apoptosis resistant E3 ubiquitin protein ligase 1.	Ribosomal protein S27a.	0.704
AREL1	ENSOMEP00000035400	ENSOMEP00000018519	ENSOMEP00000035400	Apoptosis resistant E3 ubiquitin protein ligase 1.	Ubiquitin-like domain-containing protein.	0.608
AREL1	LOC112156226	ENSOMEP00000018519	ENSOMEP00000012841	Apoptosis resistant E3 ubiquitin protein ligase 1.	Ubiquitin-like domain-containing protein.	0.598
AREL1	atg7	ENSOMEP00000018519	ENSOMEP00000018928	Apoptosis resistant E3 ubiquitin protein ligase 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.639
AREL1	fau	ENSOMEP00000018519	ENSOMEP00000028165	Apoptosis resistant E3 ubiquitin protein ligase 1.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.741
AREL1	mtx2	ENSOMEP00000018519	ENSOMEP00000000636	Apoptosis resistant E3 ubiquitin protein ligase 1.	Metaxin 2.	0.613
AREL1	mtx3	ENSOMEP00000018519	ENSOMEP00000004023	Apoptosis resistant E3 ubiquitin protein ligase 1.	Metaxin.	0.603
AREL1	trip12	ENSOMEP00000018519	ENSOMEP00000002741	Apoptosis resistant E3 ubiquitin protein ligase 1.	Thyroid hormone receptor interactor 12.	0.803
AREL1	zfand4	ENSOMEP00000018519	ENSOMEP00000002845	Apoptosis resistant E3 ubiquitin protein ligase 1.	Zinc finger, AN1-type domain 4.	0.599
ENSOMEP00000002833	AREL1	ENSOMEP00000002833	ENSOMEP00000018519	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Apoptosis resistant E3 ubiquitin protein ligase 1.	0.773
ENSOMEP00000002833	ENSOMEP00000020966	ENSOMEP00000002833	ENSOMEP00000020966	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ribosomal protein S27a.	0.999
ENSOMEP00000002833	ENSOMEP00000035400	ENSOMEP00000002833	ENSOMEP00000035400	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ubiquitin-like domain-containing protein.	0.999
ENSOMEP00000002833	LOC112156226	ENSOMEP00000002833	ENSOMEP00000012841	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ubiquitin-like domain-containing protein.	0.917
ENSOMEP00000002833	atg7	ENSOMEP00000002833	ENSOMEP00000018928	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.912
ENSOMEP00000002833	fau	ENSOMEP00000002833	ENSOMEP00000028165	Ubiquitin A-52 residue ribosomal protein fusion product 1.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.999
ENSOMEP00000002833	trip12	ENSOMEP00000002833	ENSOMEP00000002741	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Thyroid hormone receptor interactor 12.	0.989
ENSOMEP00000002833	zfand4	ENSOMEP00000002833	ENSOMEP00000002845	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Zinc finger, AN1-type domain 4.	0.999
ENSOMEP00000020966	AREL1	ENSOMEP00000020966	ENSOMEP00000018519	Ribosomal protein S27a.	Apoptosis resistant E3 ubiquitin protein ligase 1.	0.704
ENSOMEP00000020966	ENSOMEP00000002833	ENSOMEP00000020966	ENSOMEP00000002833	Ribosomal protein S27a.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.999