STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000018652Nerve growth factor receptor a (TNFR superfamily, member 16). (406 aa)    
Predicted Functional Partners:
LOC112159198
Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.
    
 0.993
LOC112144593
Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family.
    
 0.984
ripk2
Receptor-interacting serine-threonine kinase 2.
    
  0.978
LOC112143952
Neurotrophin receptor associated death domain.
  
  
 
0.974
LOC112146038
NGF domain-containing protein; Belongs to the NGF-beta family.
    
 0.971
ENSOMEP00000032916
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
    
 0.947
sort1
Sortilin.
    
 0.939
LOC112140788
Sortilin.
    
 0.939
LOC112157050
Uncharacterized protein.
    
 0.935
LOC112146024
Rho GDP dissociation inhibitor (GDI) alpha.
    
 0.935
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.