STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000020907Phosphomevalonate kinase. (274 aa)    
Predicted Functional Partners:
ENSOMEP00000001884
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
   
 
 0.968
mvk
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
   
 
 0.960
grb2
Growth factor receptor-bound protein 2b.
    
  0.725
fdps
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
   
 
 0.704
idi1
Isopentenyl-diphosphate delta isomerase 1.
   
 
 0.679
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.653
SHC3
SHC adaptor protein 3.
    
 0.653
SHC4
SHC adaptor protein 4.
    
 0.653
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
    
 
 0.628
ENSOMEP00000010591
Uncharacterized protein.
   
  0.622
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.