node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSOMEP00000007665 | ENSOMEP00000024214 | ENSOMEP00000007665 | ENSOMEP00000024214 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Origin recognition complex, subunit 5. | 0.454 |
ENSOMEP00000007665 | LOC112150272 | ENSOMEP00000007665 | ENSOMEP00000008498 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Nuclear autoantigenic sperm protein (histone-binding). | 0.731 |
ENSOMEP00000007665 | LOC112152890 | ENSOMEP00000007665 | ENSOMEP00000022840 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Retinoblastoma binding protein 4, like. | 0.894 |
ENSOMEP00000007665 | NASP | ENSOMEP00000007665 | ENSOMEP00000008683 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Nuclear autoantigenic sperm protein. | 0.731 |
ENSOMEP00000007665 | hat1 | ENSOMEP00000007665 | ENSOMEP00000023772 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. | 0.937 |
ENSOMEP00000007665 | orc2 | ENSOMEP00000007665 | ENSOMEP00000010219 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Origin recognition complex, subunit 2. | 0.472 |
ENSOMEP00000007665 | orc3 | ENSOMEP00000007665 | ENSOMEP00000027316 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Origin recognition complex, subunit 3. | 0.455 |
ENSOMEP00000007665 | rbbp4 | ENSOMEP00000007665 | ENSOMEP00000015434 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Retinoblastoma binding protein 4. | 0.894 |
ENSOMEP00000007665 | wdr73 | ENSOMEP00000007665 | ENSOMEP00000020051 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | WD repeat domain 73. | 0.839 |
ENSOMEP00000024214 | ENSOMEP00000007665 | ENSOMEP00000024214 | ENSOMEP00000007665 | Origin recognition complex, subunit 5. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.454 |
ENSOMEP00000024214 | LOC112152890 | ENSOMEP00000024214 | ENSOMEP00000022840 | Origin recognition complex, subunit 5. | Retinoblastoma binding protein 4, like. | 0.792 |
ENSOMEP00000024214 | hat1 | ENSOMEP00000024214 | ENSOMEP00000023772 | Origin recognition complex, subunit 5. | Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. | 0.975 |
ENSOMEP00000024214 | orc2 | ENSOMEP00000024214 | ENSOMEP00000010219 | Origin recognition complex, subunit 5. | Origin recognition complex, subunit 2. | 0.999 |
ENSOMEP00000024214 | orc3 | ENSOMEP00000024214 | ENSOMEP00000027316 | Origin recognition complex, subunit 5. | Origin recognition complex, subunit 3. | 0.999 |
ENSOMEP00000024214 | orc4 | ENSOMEP00000024214 | ENSOMEP00000018595 | Origin recognition complex, subunit 5. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.999 |
ENSOMEP00000024214 | rbbp4 | ENSOMEP00000024214 | ENSOMEP00000015434 | Origin recognition complex, subunit 5. | Retinoblastoma binding protein 4. | 0.792 |
ENSOMEP00000024214 | wdr73 | ENSOMEP00000024214 | ENSOMEP00000020051 | Origin recognition complex, subunit 5. | WD repeat domain 73. | 0.766 |
LOC112150272 | ENSOMEP00000007665 | ENSOMEP00000008498 | ENSOMEP00000007665 | Nuclear autoantigenic sperm protein (histone-binding). | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.731 |
LOC112150272 | LOC112152890 | ENSOMEP00000008498 | ENSOMEP00000022840 | Nuclear autoantigenic sperm protein (histone-binding). | Retinoblastoma binding protein 4, like. | 0.926 |
LOC112150272 | hat1 | ENSOMEP00000008498 | ENSOMEP00000023772 | Nuclear autoantigenic sperm protein (histone-binding). | Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. | 0.956 |