STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (526 aa)    
Predicted Functional Partners:
LOC112143258
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
 0.964
lipc
Lipase, hepatic a.
    
  0.930
ENSOMEP00000011208
24-dehydrocholesterol reductase.
    
  0.925
mogat2
Monoacylglycerol O-acyltransferase 2.
   
 
  0.910
CEL-2
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
  
  
 
0.910
lipg
Lipase, endothelial.
    
  0.903
LOC112150654
PLAT domain-containing protein.
    
  0.902
lpl
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
    
  0.899
LOC112163319
Phospholipase A(2).
   
 
 0.899
dgat2
Diacylglycerol O-acyltransferase 2.
   
 
  0.896
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.