STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOMEP00000024924Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (286 aa)    
Predicted Functional Partners:
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
0.935
ENSOMEP00000009841
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.921
LOC112147424
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.921
LOC112160885
Uncharacterized protein; Belongs to the intermediate filament family.
    
 0.913
lmna
Lamin A; Belongs to the intermediate filament family.
    
 0.902
lmnb2
Lamin B2; Belongs to the intermediate filament family.
    
 0.899
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.879
CASP6
Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.
  
  
 
0.870
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.861
ENSOMEP00000026259
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.861
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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