STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (436 aa)    
Predicted Functional Partners:
map3k2
Mitogen-activated protein kinase kinase kinase 2.
  
0.984
mapk7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.974
map3k4
Mitogen-activated protein kinase kinase kinase 4.
   
0.956
LOC112151453
Mitogen-activated protein kinase kinase kinase 22.
  
0.956
map3k3
Mitogen-activated protein kinase kinase kinase 3.
   
0.952
ksr1
Kinase suppressor of ras 1a.
   
0.933
ksr2
Kinase suppressor of ras 2.
   
 0.933
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.927
LOC112146278
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.927
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
0.915
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.