node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSOMEP00000023339 | foxred2 | ENSOMEP00000023339 | ENSOMEP00000026950 | Thioredoxin domain containing 16. | FAD-dependent oxidoreductase domain containing 2. | 0.700 |
ENSOMEP00000035079 | foxred2 | ENSOMEP00000035079 | ENSOMEP00000026950 | Myocardin related transcription factor Aa. | FAD-dependent oxidoreductase domain containing 2. | 0.667 |
ENSOMEP00000035079 | metap1d | ENSOMEP00000035079 | ENSOMEP00000033013 | Myocardin related transcription factor Aa. | Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). | 0.680 |
LOC112150458 | foxred2 | ENSOMEP00000010137 | ENSOMEP00000026950 | Kininogen 1. | FAD-dependent oxidoreductase domain containing 2. | 0.655 |
LOC112150458 | kmo | ENSOMEP00000010137 | ENSOMEP00000030003 | Kininogen 1. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.771 |
LOC112151379 | foxred2 | ENSOMEP00000000205 | ENSOMEP00000026950 | Uncharacterized protein. | FAD-dependent oxidoreductase domain containing 2. | 0.655 |
LOC112151379 | kmo | ENSOMEP00000000205 | ENSOMEP00000030003 | Uncharacterized protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.771 |
LOC112160867 | foxred2 | ENSOMEP00000020409 | ENSOMEP00000026950 | Lipase, hormone-sensitive a. | FAD-dependent oxidoreductase domain containing 2. | 0.655 |
LOC112160867 | kmo | ENSOMEP00000020409 | ENSOMEP00000030003 | Lipase, hormone-sensitive a. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.681 |
afmid | foxred2 | ENSOMEP00000011011 | ENSOMEP00000026950 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | FAD-dependent oxidoreductase domain containing 2. | 0.660 |
afmid | kmo | ENSOMEP00000011011 | ENSOMEP00000030003 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.968 |
coq3 | foxred2 | ENSOMEP00000004678 | ENSOMEP00000026950 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | FAD-dependent oxidoreductase domain containing 2. | 0.669 |
coq3 | kmo | ENSOMEP00000004678 | ENSOMEP00000030003 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.932 |
foxred2 | ENSOMEP00000023339 | ENSOMEP00000026950 | ENSOMEP00000023339 | FAD-dependent oxidoreductase domain containing 2. | Thioredoxin domain containing 16. | 0.700 |
foxred2 | ENSOMEP00000035079 | ENSOMEP00000026950 | ENSOMEP00000035079 | FAD-dependent oxidoreductase domain containing 2. | Myocardin related transcription factor Aa. | 0.667 |
foxred2 | LOC112150458 | ENSOMEP00000026950 | ENSOMEP00000010137 | FAD-dependent oxidoreductase domain containing 2. | Kininogen 1. | 0.655 |
foxred2 | LOC112151379 | ENSOMEP00000026950 | ENSOMEP00000000205 | FAD-dependent oxidoreductase domain containing 2. | Uncharacterized protein. | 0.655 |
foxred2 | LOC112160867 | ENSOMEP00000026950 | ENSOMEP00000020409 | FAD-dependent oxidoreductase domain containing 2. | Lipase, hormone-sensitive a. | 0.655 |
foxred2 | afmid | ENSOMEP00000026950 | ENSOMEP00000011011 | FAD-dependent oxidoreductase domain containing 2. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.660 |
foxred2 | coq3 | ENSOMEP00000026950 | ENSOMEP00000004678 | FAD-dependent oxidoreductase domain containing 2. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.669 |