STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spcs3Signal peptidase complex subunit 3. (180 aa)    
Predicted Functional Partners:
spcs2
Signal peptidase complex subunit 2.
   
 0.995
spcs1
Signal peptidase complex subunit 1.
   
 0.993
sec11a
Signal peptidase complex catalytic subunit SEC11.
   
 0.992
ENSOMEP00000003507
X-ray repair complementing defective repair in Chinese hamster cells 4.
   
 0.934
ENSOMEP00000018922
Inner mitochondrial membrane peptidase subunit 2.
   
 0.934
itfg2
Integrin alpha FG-GAP repeat containing 2.
   
 0.934
immp1l
Mitochondrial inner membrane protease subunit.
   
 0.934
alg2
ALG2 alpha-1,3/1,6-mannosyltransferase.
   
 
  0.796
sec63
SEC63 homolog, protein translocation regulator.
    
 
 0.728
rpn2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
   
 0.711
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.