STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3ap1Phosphoinositide-3-kinase adaptor protein 1. (836 aa)    
Predicted Functional Partners:
LOC112150138
Tyrosine-protein kinase.
    
 0.802
ENSOMEP00000025667
Spleen tyrosine kinase.
    
 0.802
pik3r3
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
     
 0.711
LOC112138447
Uncharacterized protein.
     
 0.711
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
     
 0.711
grb2
Growth factor receptor-bound protein 2b.
    
  0.686
ENSOMEP00000002349
Uncharacterized protein.
     
 0.658
ENSOMEP00000006129
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 
 0.658
LOC112147562
Uncharacterized protein.
     
 0.658
pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 
 0.658
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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