STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rab21RAB21, member RAS oncogene family. (220 aa)    
Predicted Functional Partners:
LOC112148531
Uncharacterized protein.
   
 0.983
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1.
   
 0.983
LOC112149869
RAB guanine nucleotide exchange factor (GEF) 1, like.
   
 0.983
ankrd27
Ankyrin repeat domain 27 (VPS9 domain).
   
 0.921
gapvd1
GTPase activating protein and VPS9 domains 1.
   
 0.860
ENSOMEP00000015362
Uncharacterized protein.
    
 0.775
ENSOMEP00000022164
SET binding factor 2.
    
 0.775
ENSOMEP00000031852
UDENN domain-containing protein.
    
 0.775
ENSOMEP00000027089
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.741
LOC112144507
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.730
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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