Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IW16_20980Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)    
Predicted Functional Partners:
IW16_14670
Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.913
IW16_02760
Thioester reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.899
IW16_21995
Molecular chaperone Hsp90; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.861
IW16_09840
Molecular chaperone GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.854
IW16_25680
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.849
groEL
Molecular chaperone GroEL; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; Derived by autom [...]
  
 0.791
IW16_26590
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.702
IW16_00870
50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.674
IW16_20645
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.671
IW16_07710
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.665
Your Current Organism:
Chryseobacterium vrystaatense
NCBI taxonomy Id: 307480
Other names: C. vrystaatense, CCUG 50970, Chryseobacterium sp. R-23533, Chryseobacterium sp. R-23566, Chryseobacterium vrystaatense de Beer et al. 2005 emend. Montero-Calasanz et al. 2014, LMG 22846, LMG:22846
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