STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rsub_03364DNA replication ATP-dependent helicase nuclease. (2063 aa)    
Predicted Functional Partners:
Rsub_12921
WD_REPEATS_REGION domain-containing protein.
   
 
 0.957
Rsub_05269
Exonuclease.
   
 0.925
Rsub_06407
Replication A 70 kDa DNA-binding subunit A.
    
 0.884
Rsub_06865
Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.
    
 0.884
Rsub_01530
P-loop containing nucleoside triphosphate hydrolase.
   
 0.860
Rsub_00612
Flap endonuclease GEN-like protein.
   
 0.839
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.839
Rsub_02451
DNA polymerase.
   
 0.836
Rsub_04260
DNA primase large subunit-like.
   
 
 0.819
Rsub_06007
Double-strand break repair protein.
   
 0.805
Your Current Organism:
Raphidocelis subcapitata
NCBI taxonomy Id: 307507
Other names: Kirchneriella subcapitata, R. subcapitata
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