node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | Rsub_04751 | A0A2V0P894 | A0A2V0P4A4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | Rsub_04955 | A0A2V0P894 | A0A2V0P1Y0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Piezo-type mechanosensitive ion channel component. | 0.505 |
MCM7 | Rsub_06248 | A0A2V0P894 | A0A2V0P0Y2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | TIMELESS domain-containing protein. | 0.968 |
MCM7 | Rsub_06295 | A0A2V0P894 | A0A2V0P912 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control 45. | 0.997 |
MCM7 | Rsub_07072 | A0A2V0P894 | A0A2V0P3V7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM3; Belongs to the MCM family. | 0.999 |
MCM7 | Rsub_07757 | A0A2V0P894 | A0A2V0P6Y3 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | 0.973 |
MCM7 | Rsub_08141 | A0A2V0P894 | A0A2V0P4V6 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA_pol_E_B domain-containing protein. | 0.989 |
MCM7 | Rsub_10615 | A0A2V0P894 | A0A2V0PG03 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. | 0.971 |
MCM7 | Rsub_10828 | A0A2V0P894 | A0A2V0PGG2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Swi3 domain-containing protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. | 0.971 |
MCM7 | Rsub_12921 | A0A2V0P894 | A0A2V0PKL9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | WD_REPEATS_REGION domain-containing protein. | 0.985 |
Rsub_04751 | MCM7 | A0A2V0P4A4 | A0A2V0P894 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
Rsub_04751 | Rsub_04955 | A0A2V0P4A4 | A0A2V0P1Y0 | DNA helicase; Belongs to the MCM family. | Piezo-type mechanosensitive ion channel component. | 0.697 |
Rsub_04751 | Rsub_06248 | A0A2V0P4A4 | A0A2V0P0Y2 | DNA helicase; Belongs to the MCM family. | TIMELESS domain-containing protein. | 0.964 |
Rsub_04751 | Rsub_06295 | A0A2V0P4A4 | A0A2V0P912 | DNA helicase; Belongs to the MCM family. | Cell division control 45. | 0.998 |
Rsub_04751 | Rsub_07072 | A0A2V0P4A4 | A0A2V0P3V7 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM3; Belongs to the MCM family. | 0.999 |
Rsub_04751 | Rsub_07757 | A0A2V0P4A4 | A0A2V0P6Y3 | DNA helicase; Belongs to the MCM family. | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | 0.974 |
Rsub_04751 | Rsub_08141 | A0A2V0P4A4 | A0A2V0P4V6 | DNA helicase; Belongs to the MCM family. | DNA_pol_E_B domain-containing protein. | 0.995 |
Rsub_04751 | Rsub_10615 | A0A2V0P4A4 | A0A2V0PG03 | DNA helicase; Belongs to the MCM family. | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. | 0.975 |
Rsub_04751 | Rsub_10828 | A0A2V0P4A4 | A0A2V0PGG2 | DNA helicase; Belongs to the MCM family. | Swi3 domain-containing protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. | 0.965 |
Rsub_04751 | Rsub_12921 | A0A2V0P4A4 | A0A2V0PKL9 | DNA helicase; Belongs to the MCM family. | WD_REPEATS_REGION domain-containing protein. | 0.995 |