STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C2E21_7893U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (161 aa)    
Predicted Functional Partners:
C2E21_5468
Small nuclear ribonucleoprotein Sm D2.
   
 0.990
C2E21_9547
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.989
C2E21_2373
Small nuclear ribonucleoprotein Sm D3; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
   
 0.988
C2E21_1623
Small nuclear ribonucleo-associated B.
   
 0.988
C2E21_0291
Small nuclear ribonucleoprotein G.
   
 0.988
C2E21_2794
Small nuclear ribonucleoprotein Sm D1; Involved in splicing regulation. Facilitates post- transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS. Does not participate in the production of small RNAs. Belongs to the snRNP core protein family.
   
 0.984
C2E21_0618
U1 small nuclear ribonucleo isoform B.
   
 0.984
C2E21_4487
Splicing factor 3B subunit 1.
   
 0.975
C2E21_3847
U2 small nuclear ribonucleo A.
   
 
 0.968
C2E21_9124
U2 small nuclear ribonucleo B-like.
   
 0.955
Your Current Organism:
Chlorella sorokiniana
NCBI taxonomy Id: 3076
Other names: C. sorokiniana, Chlorella sorokiniana Shihira & R.W.Krauss, Chlorella sp. C74, Chlorella sp. GXNN 01, Chlorophyta sp. LWG002615, SAG 211-8k
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