STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C2E21_61883-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (380 aa)    
Predicted Functional Partners:
C2E21_1156
Pantoate--beta-alanine ligase.
 
 0.998
C2E21_0494
Dihydroxy-acid dehydratase.
     
 0.983
C2E21_3355
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.975
C2E21_2910
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.975
C2E21_7869
Branched chain amino acid aminotransferase.
    
 0.930
C2E21_7993
Glycolate oxidase.
     
 0.775
C2E21_6204
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
     
 0.718
C2E21_5659
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
     
 0.714
C2E21_7959
Thiosulfate 3-mercaptopyruvate sulfurtransferase mitochondrial isoform X2.
    
  0.682
C2E21_2028
Delta-1-pyrroline-5-carboxylate synthase B-like isoform X1.
  
  
 0.647
Your Current Organism:
Chlorella sorokiniana
NCBI taxonomy Id: 3076
Other names: C. sorokiniana, Chlorella sorokiniana Shihira & R.W.Krauss, Chlorella sp. C74, Chlorella sp. GXNN 01, Chlorophyta sp. LWG002615, SAG 211-8k
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