STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARAM_000523GH131_N domain-containing protein. (277 aa)    
Predicted Functional Partners:
ARAM_004966
RNA polymerase II subunit 3.
    
 0.768
ARAM_005969
Serine/threonine-protein kinase.
    
 0.751
ARAM_000948
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 0.739
ARAM_003028
DNA-directed RNA polymerase I, II, and III subunit Rpb6.
    
 0.729
ARAM_003858
Putative chromatin remodeling complex subunit (Arp5); Belongs to the actin family.
    
 0.725
ARAM_002377
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
    
 
 0.723
ARAM_006993
Histone H2A; Belongs to the histone H2A family.
    
 0.691
ARAM_006666
Uncharacterized protein.
    
  0.685
ARAM_000186
Metallothionein-I gene transcription activator.
    
  0.674
ARAM_001997
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
  0.674
Your Current Organism:
Aspergillus rambellii
NCBI taxonomy Id: 308745
Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.