STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARAM_007275DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)    
Predicted Functional Partners:
ARAM_003230
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.999
ARAM_001064
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.999
ARAM_005045
DNA_mis_repair domain-containing protein.
 
 0.993
ARAM_005710
Zn(2)-C6 fungal-type domain-containing protein.
 
 0.992
ARAM_006438
Uncharacterized protein.
   
 0.981
ARAM_006790
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.977
ARAM_004614
DNA_mis_repair domain-containing protein.
 
 0.972
ARAM_007071
MutL_C domain-containing protein.
  
 0.944
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.937
ARAM_001405
DNA polymerase.
   
 
 0.903
Your Current Organism:
Aspergillus rambellii
NCBI taxonomy Id: 308745
Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.