node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARAM_001088 | ARAM_002082 | A0A0F8X1L2 | A0A0F8UE24 | Sugar isomerase, KpsF/GutQ. | Uncharacterized protein. | 0.490 |
ARAM_001088 | ARAM_003091 | A0A0F8X1L2 | A0A0F8UAG3 | Sugar isomerase, KpsF/GutQ. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.823 |
ARAM_001088 | ARAM_003569 | A0A0F8X1L2 | A0A0F8W8K1 | Sugar isomerase, KpsF/GutQ. | ABC1 domain-containing protein. | 0.878 |
ARAM_001088 | ARAM_003691 | A0A0F8X1L2 | A0A0F8UX88 | Sugar isomerase, KpsF/GutQ. | Ubiquinone biosynthesis protein. | 0.499 |
ARAM_001088 | ARAM_005065 | A0A0F8X1L2 | A0A0F8UQV4 | Sugar isomerase, KpsF/GutQ. | Zn(2)-C6 fungal-type domain-containing protein. | 0.481 |
ARAM_001088 | ARAM_007434 | A0A0F8X1L2 | A0A0F8U741 | Sugar isomerase, KpsF/GutQ. | ABC1 domain-containing protein. | 0.499 |
ARAM_001088 | COQ3 | A0A0F8X1L2 | A0A0F8UFH1 | Sugar isomerase, KpsF/GutQ. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.742 |
ARAM_001088 | COQ4 | A0A0F8X1L2 | A0A0F8UG82 | Sugar isomerase, KpsF/GutQ. | Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.642 |
ARAM_001088 | COQ6 | A0A0F8X1L2 | A0A0F8X1S9 | Sugar isomerase, KpsF/GutQ. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.856 |
ARAM_001088 | COQ7 | A0A0F8X1L2 | A0A0F8V5E4 | Sugar isomerase, KpsF/GutQ. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. | 0.850 |
ARAM_002082 | ARAM_001088 | A0A0F8UE24 | A0A0F8X1L2 | Uncharacterized protein. | Sugar isomerase, KpsF/GutQ. | 0.490 |
ARAM_002082 | ARAM_003569 | A0A0F8UE24 | A0A0F8W8K1 | Uncharacterized protein. | ABC1 domain-containing protein. | 0.515 |
ARAM_002082 | ARAM_003691 | A0A0F8UE24 | A0A0F8UX88 | Uncharacterized protein. | Ubiquinone biosynthesis protein. | 0.414 |
ARAM_002082 | COQ3 | A0A0F8UE24 | A0A0F8UFH1 | Uncharacterized protein. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.813 |
ARAM_002082 | COQ7 | A0A0F8UE24 | A0A0F8V5E4 | Uncharacterized protein. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. | 0.450 |
ARAM_003091 | ARAM_001088 | A0A0F8UAG3 | A0A0F8X1L2 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Sugar isomerase, KpsF/GutQ. | 0.823 |
ARAM_003091 | ARAM_003569 | A0A0F8UAG3 | A0A0F8W8K1 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | ABC1 domain-containing protein. | 0.540 |
ARAM_003091 | COQ3 | A0A0F8UAG3 | A0A0F8UFH1 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.850 |
ARAM_003091 | COQ4 | A0A0F8UAG3 | A0A0F8UG82 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.485 |
ARAM_003091 | COQ6 | A0A0F8UAG3 | A0A0F8X1S9 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.812 |