STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS05392.1KEOPS complex subunit Pcc1. (88 aa)    
Predicted Functional Partners:
rpoP
DNA-directed RNA polymerase, subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
    0.952
rpl37ae
Large subunit ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family.
       0.768
SIS12671.1
Bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / Tsa [...]
      
 0.715
SIS05418.1
Hypothetical protein.
       0.538
SIS05385.1
Uncharacterized membrane protein.
       0.514
Your Current Organism:
Natronorubrum thiooxidans
NCBI taxonomy Id: 308853
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.