STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACI17335.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)    
Predicted Functional Partners:
yycF
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.985
baeR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.936
ACI18100.2
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.838
ACI16989.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.790
ACI17586.1
Phosphate transporter regulatory protein PhoU; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.718
ACI17143.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.715
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
    0.550
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.510
ACI18084.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.451
ACI17642.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.420
Your Current Organism:
Coprothermobacter proteolyticus
NCBI taxonomy Id: 309798
Other names: C. proteolyticus DSM 5265, Coprothermobacter proteolyticus DSM 5265
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